Lily asked:


Does it have something to do with trying to make up what the body is lacking when you lose glucose in urine output?

Dave H asked:


Why does diabetes result in high volume of urine output?

I understand that with diabetes, the proximal tube/loop of henle/etc cannot get rid of all the excess glucose that is pumped through the nephrons, resulting in sugary urine. BUT, I don’t understand how the presence of glucose would increase the VOLUME of urine. Can someone explain?

I’m guessing it has something to do with osmosis but I can’t put my finger on it.
Paige, please don’t spam my thread ^_^